Jesika S. Faridi, PhD
Department of Physiology and Pharmacology
- Molecular and cellular physiology
- Cancer biology
- Action of insulin and insulin-like growth factors in cells
- Role of signal transduction pathways in the transition to hormone independence and drug resistance in cancer
Jesika S. Faridi earned her bachelor of science in genetics from University of California, Davis in 1995 and her doctor of philosophy in physiology from Loma Linda University in 2000. She completed a four-year postdoctoral training at Stanford University School of Medicines, Department of Molecular Pharmacology. Dr. Faridi started teaching at Pacific in 2004.
Click here to view her complete list of publications.
Targeting Ribonucleotide Reductase M2 and NF-κB Activation with Didox to Circumvent Tamoxifen Resistance in Breast Cancer.
Shah KN, Wilson EA, Malla R, Elford HL, Faridi JS.
Molecular cancer therapeutics. 2015; 14(11):2411-21.
Proline-rich AKT substrate of 40-kDa (PRAS40) in the pathophysiology of cancer.
Malla R, Ashby CR Jr, Narayanan NK, Narayanan B, Faridi JS, et al.
Biochemical and biophysical research communications. 2015; 463(3):161-6.
Genetic ablation of PRAS40 improves glucose homeostasis via linking the AKT and mTOR pathways.
Malla R, Wang Y, Chan WK, Tiwari AK, Faridi JS.
Biochemical pharmacology. 2015; 96(1):65-75.
AKT-induced tamoxifen resistance is overturned by RRM2 inhibition.
Shah KN, Mehta KR, Peterson D, Evangelista M, Livesey JC, et al.
Molecular cancer research : MCR. 2014; 12(3):394-407.
Shah KN, Faridi JS. Estrogen, tamoxifen, and Akt modulate expression of putative housekeeping genes in breast cancer cells. J Steroid Biochem Mol Biol. 2011 Jul;125(3-5):219-25. Epub 2011 Mar 21.
Shallal HM, Faridi JS, Russu WA. Anti-tumor pyrimidinylpiperazines bind to the prosurvival Bcl-2 protein family member Bcl-XL. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1325-8. Epub 2011 Jan 28.
Shah KN, Faridi JS. "Estrogen, tamoxifen, and Akt modulate expression of putative housekeeping genes in breast cancer cells." Abstract submitted to American Association for Cancer, published April 2011.
Shah KN, Faridi JS. "Identification of altered genes in tamoxifen resistant breast cancer cells overexpressing Akt." Abstract submitted to AACR Advances in Breast Cancer Research: Genetics, Biology and Clinical Applications conference, published October 2011.