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Roshanak Rahimian, PharmD, MSc, PhD



Phone: 209.946.2373
Website: PubMed


PharmD, Tehran University of Medical Sciences, Iran, 1988

MSc in Pharmacology, University of Ottawa, Canada, 1995

PhD in Pharmacology, University of British Columbia, Canada, 1998

PostDoc, Canadian Institute of Health Research, University of British Columbia, Canada, 1998-2001

Curriculum Vitae 

At Pacific Since: 2001

Roshanak Rahimian, PharmD, MSc, PhD earned her doctor of pharmacy from Tehran University of Medical Sciences in Tehran, Iran in 1988 and her master of science from the University of Ottawa in Ottawa, Canada in 1995. Dr. Rahimian earned her doctor of philosophy from University of British Columbia in Vancouver, Canada in 1998. She then completed a three-year post doctoral fellowship from the Canadian Institute of Health Research before joining the Pacific family in 2001.

Dr. Rahimian's passion for teaching is evident in everything she does. What she loves about teaching at Pacific is the student-body and the outstanding environment for active learning. It is her goal to ensure that students learn fundamental skills in her class and laboratory. Her areas of expertise are cardiovascular and endocrine physiology, pathophysiology and pharmacology.

She is a member of the American Society for Pharmacology and Experimental Therapeutics (ASPET), American Physiological Society (APS) and APS Sex and Gender Interest Group. She has served as a reviewer for the American Heart Association. Her objective as a faculty member and scholar is to fully support the students while they work to achieve their goals. She serves as the Faculty Advisor for the Alpha Xi chapter of Lambda Kappa Sigma. The individual who influenced her most in her career was her late mother.


Teaching Philosophy: "I encourage students to understand fundamental concepts and think critically. I also view teaching as central to all of my scholarly activities."


PCSP 235 - Current topics in Pharmacology and Toxicology
PHRM 123 - Physiology and Pathophysiology II
PHRM 142 - Physiology and Pathophysiology III
PHRM 145 - Pharmacology and Medicinal Chemistry II


Research Summary: "Over the past decade obesity and diabetes have reached epidemic in developed countries, and has become one of the most serious and challenging health problems in the 21st century. Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in diabetic patients. The basis of my research efforts has been several prospective population based reports providing evidence that premenopausal female becomes vulnerable to CVD in presence of diabetes. The overall goal of my studies is to elucidate the cellular and molecular mechanisms responsible for the impairment of sex-based cardiovascular protection in premenopausal diabetic females."

Research Interests: 

  • Diabetes, Estrogen and Endothelial Dysfunction
  • Sexual Dimorphism in Endothelial Function

Current Graduate Students and Visiting Scholar:

  • Farjana Akther (PhD candidates)
  • Sonali Shaligram (PhD candidate)
  • Priscilia Santiago Mora (Fulbright Scholar)

View Complete List of Publications

Selected Publications:

Shaligram.S., Sangüesa G., Akther F., Alegret M., Laguna J.C., Rahimian R.  Differential effects of high consumption of fructose and glucose on mesenteric endothelial function in female rats. Journal of Nutritional Biochemistry, 57 (2018) 136-144.
Sangüesa G., Shaligram S.,Akther F, Laguna J.C., Rahimian R1, Alegret M1. Type of supplemented simple sugar, not merely calorie intake, determines adverse effects on metabolism and aortic function in female rats. 1Equal senior authors. American Journal of Physiology, Heart Circ Physiol (2017) 312: H289-H304.
Han, X., Shaligram, S., Zhang, R., Anderson, L., and Rahimian, R. Sex-specific vascular responses of the rat aorta: Effects of moderate term (intermediate stage) streptozotocin-induced diabetes. Canadian Journal of Physiology and Pharmacology (2016) 94(4): 408-415.

Shi, H. Brown, L. M., Rahimian, R.  Sex/Gender Differences in Metabolism and Behavior: Influence of Sex Chromosomes and Hormones. International Journal of Endocrinology (2015), Article ID 24594.

Han, X., Zhang, R., Anderson, L., and Rahimian, R. Sexual dimorphism in rat aortic endothelial function of streptozotocin-induced diabetes: Possible involvement of superoxide and nitric oxide production. European Journal of Pharmacology (2014) 723 442-450.

Zhang, R., Thor, D., Han, X., Anderson, L., Rahimian, R. Sex differences in mesenteric endothelial function of streptozotocin-induced diabetic rats: A shift in the relative importance of EDRFs. American Journal of Physiology, Heart Circulatory Physiology (2012) 303: H1183-H1198.

Thor, D., Zhang, R., Anderson, L., Bose, D., Dube, G., and Rahimian, R. Effects of 17 β-estradiol on lipopolysacharride-induced intracellular adhesion molecule-1 mRNA expression and Ca2+ homeostasis alteration in human endothelial. Vascular Pharmacology (2010) 53, 230-238.

Thor, D., Uchizono, J., Lin-Cereghino, J., and Rahimian, R. The effect of 17 β-estradiol on intracellular calcium homeostasis in human endothelial cells. European journal of Pharmacology (2010) 630, 92-99.

Goel, A., Thor, D., Anderson, L., and Rahimian, R. Sexual dimorphism in rabbit aortic endothelial function under hyperglycemic conditions and gender-specific response to acute 17-beta estradiol. American Journal of Physiology- Heart Circulatory Physiology (2008) 294, H2411-2420.