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The Cheminar

Tuesday, April 25, 2023
11:00 a.m. - 12:00 p.m.

Add to Calendar 2023-04-25 11:00:00 2023-04-25 12:00:00 The Cheminar The Cheminar Paul Abbyad Ph.D. Dept. of Chem & Biochem Santa Clara University Tuesday Apr. 25th Seminar 11 AM – 12 PM Classroom Building CR 170 SIFT: Label-Free Sorting by Droplet Microfluidics Our lab has developed a novel platform for droplet sorting that can be used to sort enzymes by activity, and cells by metabolism. It is a passive technique that utilizes no excitation laser, detector, active sorter and related electronics, or fluorescent labels. It presents a robust way to sort enzyme libraries for screening and sort cancer cells by a defining characteristic, their aberrant metabolism. The technique also enables the isolation of activated T-cells prior to the display of cellular surface markers. The isolation of activated T-cells in minutes rather than hours can have broad usage as a biotechnology tool and for the study and selection for immunology and immunotherapy. About the Speaker Paul Abbyad is an associate professor in the department of Chemistry and Biochemistry at Santa Clara University. He received his BSc in Chemistry at McGill University in Montreal followed by a PhD in Chemistry from Stanford University in 2007. His dissertation investigated protein dynamics using ultrafast spectroscopy. His postdoctoral training at Ecole Polytechnique (Paris) focused on applying droplet microfluidics to the study of sickle cell disease. He joined Santa Clara University in 2012, where his research program uses microfluidic platforms for the analysis of chemical and biological systems. He is a recipient of an NSF CAREER award and a Henry Dreyfus Teacher-Scholar award. 3601 Pacific Ave, Stockton, CA 95211, USA College of the Pacific College of the Pacific America/Los_Angeles public

The Cheminar

Paul Abbyad

Ph.D. Dept. of Chem & Biochem

Santa Clara University

Tuesday Apr. 25th Seminar 11 AM – 12 PM Classroom Building CR 170

SIFT: Label-Free Sorting by Droplet Microfluidics Our lab has developed a novel platform for droplet sorting that can be used to sort enzymes by activity, and cells by metabolism. It is a passive technique that utilizes no excitation laser, detector, active sorter and related electronics, or fluorescent labels. It presents a robust way to sort enzyme libraries for screening and sort cancer cells by a defining characteristic, their aberrant metabolism. The technique also enables the isolation of activated T-cells prior to the display of cellular surface markers. The isolation of activated T-cells in minutes rather than hours can have broad usage as a biotechnology tool and for the study and selection for immunology and immunotherapy.

About the Speaker Paul Abbyad is an associate professor in the department of Chemistry and Biochemistry at Santa Clara University. He received his BSc in Chemistry at McGill University in Montreal followed by a PhD in Chemistry from Stanford University in 2007. His dissertation investigated protein dynamics using ultrafast spectroscopy. His postdoctoral training at Ecole Polytechnique (Paris) focused on applying droplet microfluidics to the study of sickle cell disease. He joined Santa Clara University in 2012, where his research program uses microfluidic platforms for the analysis of chemical and biological systems. He is a recipient of an NSF CAREER award and a Henry Dreyfus Teacher-Scholar award.