The Cheminar: John F. Hartwig, Ph.D.
The Cheminar: John F. Hartwig, Ph.D.
11:00 a.m. - 12:00 p.m.
Join us for the next Cheminar featuring John F. Hartwig, Ph.D.
Tuesday, Jan. 30 | 11 a.m. – 11:59 a.m.
Classroom Building 170
From Prozac to perfume, sustainable plastics to solar energy, catalysis enables our current standard of living and controls our potential to progress sustainably. The reduced emissions of modern cars, the abundance of fresh food at our stores, the beginnings of green energy, and the new pharmaceuticals we use to treat disease are made possible by chemical reactions controlled by catalysts.
Research in our group has sought to design catalysts that can introduce and manipulate functional groups in both small and large organic molecules. These reactions include novel coupling processes(1) to facilitate the synthesis of medicinally important molecules, and reactions that enable the introduction of functional groups into positions of molecules inaccessible by classical organic reactions.(2, 3)
This lecture will introduce the importance of catalysis overall, some major challenges in the field, and ways that our group is seeking to address these challenges. Examples of important catalysts used today, and examples of strategies to discover and develop new classes of catalysts for future applications will be presented.
References:
1. J. F. Hartwig, K. H. Shaughnessy, S. Shekhar, R. A. Green, in Organic Reactions, S. E. Denmark, Ed. (John Wiley & Sons, Winheim, 2020), vol. 100, chap. 14, pp. 853-958 2. I. A. I. Mkhalid, J. H. Barnard, T. B. Marder, J. M. Murphy, J. F. Hartwig, C−H Activation for the Construction of C−B Bonds. Chem. Rev. 110, 890-931 (2010). 3. S. N. Natoli, J. F. Hartwig, Noble−Metal Substitution in Hemoproteins: An Emerging Strategy for Abiological Catalysis. Acc. Chem. Res. 52, 326-335 (2019).
